Available immediately, Suite 406 at 100 Crosby Street presents a rare opportunity to lease an impeccably built, fully-operational medical suite in the heart of SoHo. Measuring 2,375 RSF, this turnkey space delivers a private and professional clinical environment with high-end finishes, excellent light, and a logical flow for daily operations.

The suite is efficiently configured with seven fully plumbed treatment rooms, a generous reception and waiting area, an oversized storage closet for inventory and equipment, and a dedicated administrative office tucked discreetly toward the rear. High 11-foot ceilings lend the space a sense of openness, while large operable windows provide natural light throughout the day. The unit boasts direct elevator access, giving the space both prominence and convenience for patients and practitioners alike.

The building itself offers a newly renovated attended lobby that combines cast-iron detail with modern amenities, setting an elegant tone upon entry. Located on the corner of Crosby and Prince, the address enjoys a highly desirable downtown footprint, surrounded by boutique retail, luxury wellness, and some of New York’s most prominent hospitality concepts. Transit access is unbeatable, with the B/D/F/M/R/W/6 subway lines all within a few blocks.

Ideal for dermatologists, wellness clinics, OB/GYN, or private specialists, Suite 406 is delivered in move-in condition with a sublease term extending through June 2033—providing long-term security in one of Manhattan’s most supply-constrained medical corridors.

For tenants seeking an immediate, functional, and high-design home for their practice in SoHo, 100 Crosby Street Suite 406 stands as a best-in-class offering. Showings by appointment only.