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501 Fifth Ave. 12th Floor Medical Space
- 1,420 SQFT
- Lease Term Negotiable
-
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Introducing a prime medical office space comprising 1,420 square feet available for rent at the prestigious address of 501 Madison Avenue in the heart of Manhattan, New York. This turnkey-ready office space is tailor-made for medical practitioners, offering a beautifully built-out environment designed to enhance the patient experience. The layout includes four examination rooms with sinks and an on-site X-ray unit, making it ideal for various healthcare practices.
The office features a bright and airy reception/waiting area, providing a welcoming atmosphere for patients. Tenant-controlled air conditioning ensures a comfortable environment, and the space benefits from ample natural light, thanks to numerous windows facing 42nd Street. This move-in-ready medical office is in excellent condition, allowing healthcare professionals to start practicing immediately. Sublease or lease assignment options are available for up to six more years, providing flexibility for your practice.
501 Madison Avenue is equipped with modern amenities and infrastructure, ensuring efficient operations and seamless connectivity. The building is under 24/7 security and management, providing a safe and secure working environment for practitioners. Its central location offers easy access to renowned medical institutions and major transportation hubs, making it convenient for both practitioners and patients.
This exceptional medical office space presents a unique opportunity to establish or expand your healthcare practice in the heart of Manhattan, surrounded by a vibrant healthcare community. Don't miss the chance to be part of this prestigious address and provide top-notch healthcare services in a professionally designed and well-equipped setting.
View / Download Floor Plan HERE
Space Features:
- (4) Exam Rooms
- X-Ray Unit
- (1) Private Office
- Reception with Guest Seating
- Filing Station
- Hardwood Flooring
- Windows at 2 Sides
- Higher Floor with Natural Light
Property Facts:
- Building Type: Office
- Year Built: 1916
- Building Height: 23 Stories
- Building Size: 152,361 SF
- Building Class: B
- Typical Floor Size: 6,300 SF
- Unfinished Ceiling Height: 12'
- Parking: Surface and Covered Parking
- Transportation: Easily accessible by bus and subway lines
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501 05 Ave
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About the Building
The Astor Trust Building | Landmark Office Destination in Midtown Manhattan
Located at the corner of Fifth Avenue and 42nd Street, directly across from the New York Public Library and Bryant Park, 501 Fifth Avenue stands as one of Midtown Manhattan’s most recognizable commercial office towers. Known as The Astor Trust Building, this historic 23-story property delivers a refined blend of classic pre-war architecture and modern professional functionality, making it a sought-after address for boutique financial firms, law practices, and medical professionals alike.
Built in 1916 and comprising approximately 152,000 square feet of office space, the building features gracious ceiling heights, elegant stonework, and oversized windows that frame iconic views of Fifth Avenue and the surrounding cityscape. Suites range from 955 to 21,933 square feet, with floorplates around 6,300 square feet, offering full-floor and partial-floor availability. Several units are move-in ready with full build-outs in place, including corner offices, internal meeting rooms, pantries, and furnished reception areas.
Tenants enjoy a prestigious setting with 24-hour access, on-site property management, and a dedicated lobby attendant. The building is equipped with modern conveniences such as an electronic directory, passenger elevators, and reserved parking. It is steps from Grand Central Terminal and the Times Square–Port Authority transit complex, ensuring exceptional accessibility via subway, Metro-North, and regional bus lines.
Professionals leasing space here benefit not only from the premier location and distinctive ambiance but also from the building’s long-standing reputation for stability and service. Current tenants include notable investment groups, healthcare providers, and high-end beauty service firms.
With its architectural grandeur, unbeatable Fifth Avenue address, and flexible leasing options, 501 Fifth Avenue remains one of the most prestigious and enduring office destinations in New York City’s Midtown corridor.
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